Yen-Yi Zhen Selected Research

Therapeutics

3/2021	Targeting Pin1 for Modulation of Cell Motility and Cancer Therapy.
6/2016	Combined Therapy With Adipose-Derived Mesenchymal Stem Cells and Ciprofloxacin Against Acute Urogenital Organ Damage in Rat Sepsis Syndrome Induced by Intrapelvic Injection of Cecal Bacteria.
1/2016	Exendin-4 therapy still offered an additional benefit on reducing transverse aortic constriction-induced cardiac hypertrophy-caused myocardial damage in DPP-4 deficient rats.
12/2015	Early Administration of Carvedilol Protected against Doxorubicin-Induced Cardiomyopathy.
11/2015	Combined melatonin and exendin-4 therapy preserves renal ultrastructural integrity after ischemia-reperfusion injury in the male rat.
1/2015	Mixed serum-deprived and normal adipose-derived mesenchymal stem cells against acute lung ischemia-reperfusion injury in rats.
1/2014	Extracorporeal shock wave therapy ameliorates cyclophosphamide-induced rat acute interstitial cystitis though inhibiting inflammation and oxidative stress-in vitro and in vivo experiment studies.
1/2014	Prompt bone marrow-derived mesenchymal stem cell therapy enables early porcine heart function recovery from acute myocardial infarction.
11/2013	Benefit of combined therapy with nicorandil and colchicine in preventing monocrotaline-induced rat pulmonary arterial hypertension.
5/2013	Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia-reperfusion injury.

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Yen-Yi Zhen Research Topics

Disease

9	Inflammation (Inflammations) 11/2020 - 07/2012
8	Ischemia 01/2017 - 03/2013
6	Reperfusion Injury 11/2015 - 03/2013
5	Neoplasms (Cancer) 02/2022 - 01/2015
4	Fibrosis (Cirrhosis) 01/2020 - 01/2014
4	Infarction (Infarctions) 01/2015 - 10/2013
3	Pulmonary Arterial Hypertension 05/2016 - 11/2013
3	Heart Failure 01/2016 - 01/2015
3	Myocardial Infarction 05/2014 - 10/2013
2	Lung Neoplasms (Lung Cancer) 11/2020 - 01/2019
2	Shock 01/2017 - 01/2014
2	Sepsis (Septicemia) 06/2016 - 01/2014
2	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 06/2016 - 12/2012
1	Nephrotic Syndrome (Syndrome, Nephrotic) 11/2020
1	Arteriolosclerosis 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Kidney Neoplasms (Kidney Cancer) 04/2019
1	Carcinoma (Carcinomatosis) 04/2019
1	Renal Cell Carcinoma (Grawitz Tumor) 04/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 04/2019
1	Congenital Abnormalities (Deformity) 01/2019
1	Status Epilepticus (Complex Partial Status Epilepticus) 12/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 12/2016
1	Lung Injury 05/2016
1	Cardiomegaly (Heart Hypertrophy) 01/2016
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2016
1	Cardiomyopathies (Cardiomyopathy) 12/2015
1	Necrosis 05/2015
1	Carotid Stenosis (Carotid Artery Stenosis) 05/2015
1	Gliosis 05/2015
1	Cognitive Dysfunction 05/2015
1	Hypertrophy 01/2014
1	Hematuria 01/2014
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 01/2014
1	Hypoxia (Hypoxemia) 01/2014
1	Acute Lung Injury 01/2014

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 11/2020 - 07/2012
7	Caspase 3 (Caspase-3)IBA 06/2016 - 07/2012
7	Biomarkers (Surrogate Marker)IBA 05/2016 - 01/2014
6	salicylhydroxamic acid (SHAM)IBA 01/2017 - 01/2014
4	Exenatide (Byetta)FDA Link 01/2017 - 10/2013
4	Matrix Metalloproteinases (MMPs)IBA 05/2016 - 05/2014
4	MelatoninIBA 11/2015 - 03/2013
4	Messenger RNA (mRNA)IBA 05/2015 - 07/2012
3	Interleukin-6 (Interleukin 6)IBA 11/2020 - 07/2012
3	CreatinineIBA 11/2020 - 06/2016
3	AntioxidantsIBA 01/2017 - 07/2012
3	Cytochromes c (Cytochrome c)IBA 05/2016 - 09/2015
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 01/2014
2	Focal Adhesion Protein-Tyrosine KinasesIBA 02/2022 - 01/2019
2	AlbuminsIBA 11/2020 - 01/2014
2	Phosphotransferases (Kinase)IBA 01/2019 - 06/2016
2	Sitagliptin Phosphate (Januvia)FDA Link 05/2015 - 10/2013
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 02/2022
1	Pharmaceutical PreparationsIBA 03/2021
1	Desoxycorticosterone Acetate (DOCA)FDA Link 01/2020
1	SaltsIBA 01/2020
1	Lamin Type A (Lamin A)IBA 01/2019
1	6- (4- (3- (methylsulfonyl)benzylamino)- 5- (trifluoromethyl)pyrimidin- 2- ylamino)- 3,4- dihydroquinolin- 2(1H)- oneIBA 01/2019
1	Sirolimus (Rapamycin)FDA Link 01/2017
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2017
1	Neuroprotective AgentsIBA 12/2016
1	Dynamins (Dynamin)IBA 12/2016
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 06/2016
1	NADPH Oxidases (NAD(P)H oxidase)IBA 06/2016
1	Ciprofloxacin (Cipro)FDA LinkGeneric 06/2016
1	CalciumIBA 05/2016
1	Therapeutic UsesIBA 05/2016
1	Peptides (Polypeptides)IBA 05/2016
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2016
1	EnzymesIBA 01/2016
1	AngiopoietinsIBA 01/2016
1	DNA (Deoxyribonucleic Acid)IBA 01/2016
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2016
1	Carvedilol (Coreg)FDA LinkGeneric 12/2015
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 12/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2015
1	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2015
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 09/2015
1	Monocyte Chemoattractant ProteinsIBA 05/2015
1	N 30IBA 01/2015
1	CateninsIBA 01/2015
1	Liposomes (Liposome)IBA 01/2014
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2014
1	CollagenIBA 01/2014
1	Substance PIBA 01/2014
1	Interleukin-12 (IL 12)IBA 01/2014
1	Chemokine CCL5IBA 01/2014
1	Small Interfering RNA (siRNA)IBA 01/2014
1	Transient Receptor Potential ChannelsIBA 01/2014
1	LipofectamineIBA 01/2014
1	Macrophage Migration-Inhibitory FactorsIBA 01/2014
1	Nicorandil (SG 75)IBA 11/2013
1	Colchicine FDA LinkGeneric 11/2013
1	MonocrotalineIBA 11/2013

Therapy/Procedure

12	Therapeutics 03/2021 - 12/2012
4	Ligation 05/2014 - 12/2012
2	Punctures 01/2014 - 12/2012
1	Nephrectomy 04/2019
1	Extracorporeal Shockwave Therapy 01/2014